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Persistent elevation should prompt an evaluation for occult disease once intake and interference have been excluded, and red flags such as unexplained weight loss or findings specific to organs are present

Personalizing breast cancer screening based on polygenic risk and family history

Melatonin has demonstrated some protective effects on esophageal tissue in research settings

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"Even people that are pretty healthy, boy, they're thinking about [GLP-1s] because my patients are rational and they understand this is evidence-based, and it does seem to have some longevity benefit." He doesn't broadly recommend the entire class of compounds, though