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B., Martin, S

Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility In a 2-year carcinogenicity study in CD-1 mice, subcutaneous doses of 0.3, 1 and 3 mg/kg/day [9-, 33- and 113- fold the maximum recommended human dose (MRHD) of RYBELSUS 14 mg, based on AUC] were administered to the males, and 0.1, 0.3 and 1 mg/kg/day (3-, 9- and 33-fold MRHD) were administered to the females

Although it's still in clinical trials and not yet FDA approved, its trial results are highly promising

Mass, E, Ballesteros I, Farlik M, Halbritter F, Gnther P, Crozet L, et al

Native GLP-1 Control Provides a reference agonist for GLP-1R assays