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Recent research suggests that metformin may also alter the gut microbiota, through the protection of the intestinal barrier, promotion of SCFAs producing bacteria growth, regulation of bile acids plasmatic levels and their excretion, and direct regulation of growth of bacteria with a positive effect on glucose homeostasis (eg., Akkermansia muciniphila ) (Zhang and Hu, 2020)

This protocol delivers the same active pharmaceutical ingredients as brand medications but through a compounding model that eliminates unnecessary markup

Adequate hydration (at least 2-3 liters daily), fiber supplementation, and magnesium citrate at bedtime are the first-line approaches

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[DOI] [PubMed] [Google Scholar] 98.St Onge EL, Miller SA