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PRP works best when follicles are still present but becoming weaker, smaller, or less productive

However, the combined use of both drugs shows a more significant effect in inhibiting AKT and activating AMPK (Fig

Oxidative stress is another critical factor, with excess ROS damaging trophoblast cells and leading to placental insufficiency

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PLoS ONE 9, e109540 10.1371/journal.pone.0109540 [DOI] [PMC free article] [PubMed] [Google Scholar] 45.Ryder, J.W., Yang, J., Galuska, D., Rincn, J., Bjrnholm, M., Krook, A.et al