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Hypoxia at the injury site resolves faster with improved perfusion, removing the oxygen-deficit barrier to fibroblast metabolism

This hormonal deficit contributes to poor growth and development in children, and in adults fails to maintain essential aspects of bodily form and function that are needed for a healthy life of normal duration

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Elevated fasting insulin, visceral adiposity, non-alcoholic fatty liver disease, and chronic systemic inflammation are not merely cardiovascular or endocrine risk factors they represent a hostile cellular environment in which neoplastic transformation is more likely to occur, progress, and evade immune surveillance

Nonalcoholic fatty pancreas disease: role in metabolic syndrome, prediabetes, diabetes and atherosclerosis