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For instance, zinc deficiency has been associated with insulin resistance and impaired glucose metabolism, both of which are common in PCOS 15,17

Body Composition and Weight Considerations Obesity impairs growth hormone dynamics through multiple mechanisms including increased free fatty acids suppressing secretion, inflammatory cytokines from adipose tissue, and reduced receptor sensitivity

They work by mimicking the natural GLP-1 hormone, which helps regulate blood sugar, appetite, and satiety

The third is if a patient has a BMI of 27 or higher plus pre-diabetes, a history of heart attack or stroke, or symptomatic peripheral artery disease

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