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Pregnant or breastfeeding women should avoid these treatments, and regular medical supervision is crucial to monitor side effects and ensure safe use

GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering

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GLP-1 agonist benefits are multiple regarding blood glucose control in the form of reducing Hemoglobin A1c (HBA1c) by 1.1%-1.6%, reducing postprandial excursions, and decreasing weight

Both the reductions in HbA1c and FPG were larger in DPP-4is than those in acarbose (Figures 2B,C)