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This unbalance is in keeping with our PsA cohort clinical features, in which the most recorded metabolic comorbidities (see Table 1) were obesity (35.9%), hypertension (23.1%), hypercholesterolemia (12.8%), DT2 (15.4%) and metabolic syndrome (15.4%)

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Pyknosis Condensation of the nucleus and chromatin, often observed in cells undergoing cell death

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4F) and promoted nuclear translocation of -catenin and downstream Myc expression in DPCs (Fig