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About this article Cite this article TeSlaa, T., Ralser, M., Fan, J

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Indeed, there are multiple primary or secondary bile acid chemosensors in the liver (348, 354) or scattered along the gastrointestinal tract (355), where they ensure a direct negative feedback aiding detoxification (356) and protecting from hepatotoxicity and carcinogenicity displayed by some secondary bile salt such as lithocholic acid

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