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Not everyone is comfortable with needles, and the thought of regular injections can be daunting

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Two authors independently conducted all data analyses, with data extraction performed using SQLiteStudio ( version 3.3.3 ) and statistical analyses conducted in IBM SPSS Statistics ( version 27.0 ) and R software ( version 4.3 )

One of the most debilitating and defining hallmarks of ME/CFS and Long COVID is post-exertional malaise (PEM), a severe, disproportionate exacerbation of symptoms following even minor physical, cognitive, or emotional exertion