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They are available solely as research chemicals intended for laboratory research purposes
MensbergPNybySJorgensenPGStorgaardHJensenMTSivertsenJet al
155 The majority of current studies have focused on short-term effects, leaving the long-term effects ambiguous
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In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations
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