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10.1073/pnas.0600865103 Proc Natl Acad Sci U S A

10.1210/jc.2002-021479 21

You start low and increase slowly to give your body time to adjust

The tradeoff is that this aggression comes with more potential for side effects: elevated heart rate, anxiety, disrupted sleep, crashes, and dependency if used without appropriate cycling

If methylation is going gangbusters and cysteine is donating plenty of sulphites, this can result in some major issues, including neurological symptoms and allergies, as well as interacting with histamine intolerance