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Conclusion Oral GLP-1 therapy is entering a new phase as food and water restrictions are removed

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Next, we observed that the MLV-based pseudovirus system had very low transduction efficiency in cell lines that endogenously express TMPRSS2, such as Calu-3 and Caco-2 cells (data not shown)

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The mechanism likely involves mitochondrial energy metabolism, as migraineurs often show impaired mitochondrial function in brain tissue