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Temperature is the variable most people underestimate When pharmacists say "room temperature," they mean a controlled environment between 68 and 77 degrees Fahrenheit (20 to 25 degrees Celsius), with allowable excursions up to 86 degrees Fahrenheit (30 degrees Celsius)

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In parallel, IMC treatment resulted in marked reductions in the intestinal sterol transporter NiemannPick C1-like 1 (NPC1L1) and reorganization of the gut microbial community, primarily reversing choline-supplemented diet-induced changes