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Interfering with the skin can cause scarring or infection and may affect pigment removal

B12 is crucial for red blood cell formation, neurological health, DNA synthesis, energy metabolism, and mood regulation

(4) Single route of administration: the current preclinical animal studies and clinical human trials predominantly employ oral administration as the primary intervention method for BBR, with a notable lack of research on alternative delivery approaches such as transdermal absorption

Compound danshen dripping pill, Huangqi Baihe granules, salidroside, ginsenoside Rg1 and tetrahydrocurcumin have better ability in anti-AMS