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doi: 10.1016/j.tins.2020.06.002 440 BensonCAWongGTenorioGBakerGBKerrBJ

Phase 2 showed significant improvement over placebo Time to response: Potentially faster than SSRIs (AMPA modulation) Source Why it might interest you: AMPA modulation is a novel, non-monoaminergic mechanism with potential for faster onset and fewer side effects (notably less sexual dysfunction and weight gain) than standard antidepressants

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