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Pair with a hypocaloric, proteinforward diet tailored to energy needs

This sided with the mentioned safety evidence, as BPC 157 exhibited a general lack of toxicity

Inhibitory effect of somatostatin on insulin secretion is not mediated via the CNS

Further, BPA is lipophilic 8 and able to cross both the blood brain barrier 9 and the placenta, the latter resulting in measurable levels in fetal blood samples 10,11

This is most relevant for weight-based peptides like kisspeptin (dosed in mcg/kg) and less relevant for receptor-saturating peptides like BPC-157, where tissue concentration at the injury site matters more than total body distribution