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People with a history of certain medical conditions, such as pancreatitis or medullary thyroid carcinoma, may need alternative treatment options for weight management
[DOI] [PMC free article] [PubMed] [Google Scholar] 125.Burns J., Yokota T., Ashihara H., Lean M.E.J., Crozier A
The opposing physiological actions of ghrelin, compared to insulin and GLP-1, may justify the opposite direction of changes in response to cannabis in this study, i.e., increase in ghrelin levels, compared to decrease in insulin and GLP-1 levels
The term malignant melanoma is synonymous with melanoma : there is no such thing as a benign melanoma
Together, these aspects warrant caution in the chronic use of GLP-1 receptor agonists during periods of active growth and maturation, reinforcing the need for long-term, sex-stratified studies to ensure safe and effective therapeutic application
