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These oocytes exist in dormant follicles until activated by cyclical hormone signals after puberty

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Inflammopharmacology 16:19 Bayliss JA, Lemus MB, Santos VV, Deo M, Davies JS, Kemp BE, Elsworth JD, Andrews ZB (2016) Metformin prevents nigrostriatal dopamine degeneration independent of AMPK activation in dopamine neurons

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