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Important distinction: chronic insomnia is assessed through sleep onset, awakenings, total sleep time, sleep efficiency, daytime effects and patient experience

Reusing injection supplies increases infection risk, causes needle dulling that makes injections more painful, and can introduce contaminants into the vial

People with insulin resistance, thyroid conditions, or other hormonal factors may see a modified response curve compared to the trial averages

Diagnosis typically involves a combination of clinical assessment, laboratory tests, and imaging studies (ultrasound abdomen, magnetic resonance elastography) with liver biopsy remaining the gold standard for staging of hepatitis and hepatic fibrosis

Science 376 , 14711476 (2022)