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While formal pharmacokinetic studies of GLP-1RA co-administration with these IBD drugs have not been conducted, clinicians should monitor for unexplained changes in therapeutic response, particularly during GLP-1RA initiation and dose escalation, and consider staggering oral medications when feasible

It has been demonstrated that various pathological processes, including malignancy (Wang et al., 2022), neurodegenerative diseases (Tao et al., 2020), and liver diseases (Kim et al., 2020), are correlated with dysregulated ferroptosis

In the human condition Fanconi Anaemia, metabolic ROS were shown to induce DNA damage in hematopoietic stem cells (HSCs) when they start cycling to exit quiescence, which impairs blood production in FancA / mice 51

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