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Se ha demostrado que en pacientes con DM2 la respuesta al efecto incretina est alterada14 como resultado de un severo defecto de la sensibilidad para el GIP en la clula Beta y de reduccin en la secrecin de GLP-1 inducida por alimentos15

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Follow-Up and Monitoring Follow-Up and Monitoring Your medical service professional might arrange subsequent appointments to observe how your skin responds to treatment modifications and provide additional advice if required

Patients who experience severe diarrhea (more than six watery stools per day, signs of dehydration, inability to maintain fluid intake) within the first two weeks at a new dose should contact their prescribing physician