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J Allergy Clin Immunol Pract 7(1):336338 Monge-Ortega OP, Cabanas R, Fiandor A, Dominguez-Ortega J, Gonzalez-Munoz M, Quirce S, Lluch-Bernal M, Bellon T (2018) Overlap Between DRESS syndrome and exanthema induced by sulfadiazine in a patient treated with sulfamethoxazole: utility of the lymphocyte transformation test for identification of the culprit drug

These molecules retain a phloroglucinol scaffold fused to terpenoid moieties, and their hybrid architecture likely supports multiple mechanisms of action, including membrane destabilization and oxidative stress induction

GPx4 is also considered a tumor suppressor because it is down-regulated in tumors [23, 43]

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