A4: Because they act on different receptor pathways related to GH-axis regulation, researchers may evaluate them together to study combined signaling behavior and pathway interaction in controlled models
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5 for a graphical summary of the main results of the study), confirming their requirement for agonist-induced GLP-1R phosphorylation, and identifying the third serine doublet at position 451/452 as required for the recruitment of GRK2 to the stimulated receptor, as well as unveiling a previously unknown positive correlation between receptor phosphorylation and its capacity for cAMP generation downstream of GLP-1 stimulation in -cells
Glucose deficit triggers tau pathology and synaptic dysfunction in a tauopathy mouse model
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