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Cloning and functional expression of a human glucagon-like peptide-1 receptor

In Supplemental Figure 11, we hypothesize how semaglutide may regulate BW by affecting neuronal input to the PB from several independent brain nuclei, including the AP and ARH, both direct targets of semaglutide

Originally developed to treat type 2 diabetes, it works by activating receptors in the pancreas to increase insulin release and reduce glucagon a hormone that raises blood sugar

The primary objective was to investigate safety and tolerability of LY3298176

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