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Hypokalemia (low potassium) In rare cases, excessive B12 therapy can affect potassium levels.

On the day of the assay, serial dilutions (7-fold dilutions, 7 concentrations per compound and one well containing only assay buffer) of test compounds were performed in duplicate in assay buffer to appropriate concentrations in 96-well plates (Greiner, U-shape #GR-650201) using a Biomek i7 liquid handler

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Its also possible that these associations have nothing to do with vitamin B12 and rather that it is an innocent bystander