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Most people see dramatic weight loss in around 1-2 months

To address this limitation, GLP-1 RAs, such as albiglutide, dulaglutide, exenatide, liraglutide, lixisenatide, and semaglutide, have been developed as synthetic analogs of GLP-1 that resist DPP-4-mediated degradation

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He also noted that the benefits of these adjunctive therapies on blood glucose management and kidney- and heart-related disease reduction are well-documented, and that several major medical organizations, like the American Heart Association and American Society of Nephrology, have even changed their guidelines to include these medications

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