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Endoscopy may be recommended in some cases, but is not routinely required for all patients

Persistent emotional flattening, reduced pleasure or a noticeable change in motivation should be discussed with the prescribing clinician particularly if it is affecting relationships, work or everyday life

The specialty societies are working on development of consensus instructions for implementation of this coding change

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Gastrointestinal adverse events were more commonly observed in patients receiving resmetirom, but diarrhea was self-limited and did not promote drug withdrawal