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Crucially, the hydrogel matrix protects insulin from gastric degradation while enabling pH-triggered release in intestinal alkaline environments, thereby mimicking the kinetics of physiological insulin secretion

Those with significant gastrointestinal symptoms, in the dose-escalation phase, or with other risk factors may benefit from specific precautions

Gastroparesis burping occurs when the stomach muscles move food too slowly, causing it to sit longer than normal and leading to symptoms such as bloating, early fullness and discomfort after eating. Most people on GLP-1s never run into this issue, especially if their doctor increases dosing gradually

After the initial treatment period, maintenance doses may be given less frequently