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Weight Loss Results with Rybelsus: While not FDA-approved for weight loss, clinical trials showed: 3 mg dose: 1-2% body weight loss 7 mg dose: 2-3% body weight loss 14 mg dose: 3-5% body weight loss Compare to injectable semaglutide (Wegovy): 2.4 mg weekly injection: 10-15% body weight loss The difference: Injectable semaglutide produces 3-5 times more weight loss than oral semaglutide at maximum doses

[DOI] [PMC free article] [PubMed] [Google Scholar] Considine MJ, Foyer CH

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GLP-1RAs further lower the risk of stroke indirectly by reducing traditional stroke risk factors such as HbA1c, SBP, body weight, and dyslipidemia