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The single human musculoskeletal paper that gets cited often is a small retrospective case series of intra-articular BPC-157 injections for multiple types of knee pain. It reported improvement in 11 of 12 patients, but the study has major limitations: no control group, no standardized objective outcome measures, no imaging confirmation of pathology, and unclear diagnostic specificity

It reduces post-injury fibrosis by modulating the expression of matrix metalloproteinases (MMPs), promotes the formation of new blood vessels, and stimulates muscle fiber regeneration

Castiglioni, A

Demir Y, Isk M, Gulcin I, Beydemir S (2017) Phenolic compounds inhibit the aldose reductase enzyme from the sheep kidney

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