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Next, the extracted features were identified with an analysis based on UHPLC-FTMS (Orbitrap Fusion, Thermo Fisher Scientific)

This is consistent with the Research Domain Criteria (RDoC) approach advanced by the National Institute of Mental Health (Table 1

In this context, it has been shown that bisphenol-A can alter the perinatal chloride shift, a critical period during development where the cytosolic concentration of chloride downs from 100 to 20 mM (Rivera et al., 1999)