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Regulatory status for compounded substances can change which is one reason clinical observers caution against building long-term treatment plans around compounds that lack formal approval

Compounding BPC-157: A regulatory loophole In a statement, Health Canada said BPC157 has not been authorized, its safety, efficacy, and quality have not been assessed and there is limited scientific evidence to support its use, including a lack of established human dosing protocols

An appropriate separation between the ingestion of levothyroxine and soy protein-based compounds should be advised to warrant a proper absorption of the hormone [154]

Stability and delivery are still issues for peptide therapy

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