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Retatrutide and triple agonism In a Phase 2 trial published in the New England Journal of Medicine, adults with obesity who received the highest studied retatrutide maintenance dose had a mean body-weight reduction of 24.2% after 48 weeks

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(2022) LY3437943, a novel triple glucagon GIP and GLP-1 receptor agonist for glycemic control and weight loss From discovery to clinical proof of concept