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PD-L1 is an immune checkpoint protein frequently overexpressed in tumor cells across various solid malignancies, including lung cancer, melanoma, and gastric carcinoma

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Additionally, CS exposure also disrupts the extracellular matrix during COPD (Shapiro and Ingenito, 2005), which could subsequently promote FAO in EpiC (Schafer et al., 2009)

Despite extensive preventive efforts, over one billion people worldwide were affected by obesity in 2022 [1]

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