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Elevated levels of angiotensin-converting enzyme 2 (ACE2) expression are associated with producing various coronavirus peptidases

TRP, as an NAD + precursor, is first converted to quinolinic acid (QA) through a 5-step enzymatic reaction and then to nicotinic acid mononucleotide (NAMN) under the action of quinolinic acid phosphoribosyl transferase (QPRT)

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