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In another study, response to escitalopram was associated with higher plasma baseline 5-HT levels, lower baseline KYN/TRP and QA/TRP ratios, and, among remitters, a treatment-related increase in the KYNA/3-HK ratio [193]

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Also, substances such as vascular endothelial growth factor (VEGF) and transforming growth factor-beta (TGF- ), released by astrocytes enhance BBB formation and maintenance (Daneman, 2008

Heres a general overview of the dosage: Initial Phase : Dosage : 600 to 1200 mg per week Frequency : 1 to 2 injections per week Duration : 1 to 3 months Maintenance Phase : Dosage : 600 to 1200 mg per month Frequency : 1 injection per month Duration : Ongoing, based on desired results Administration Methods: Intravenous (IV) Injection/Drip: