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Moreover, melancholic depression is marked by elevated KYN/TRP ratios [48], and KYNA/QA ratios inversely correlate with anhedonia severity [49]

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HS-GC/MS analyses Blood and tissue concentrations of EtOH and acetaldehyde from pharmacokinetics study and at the end of 6-wk ethanol feeding regimen were determined by HS-GC/MS as described 56