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L-DOPA induced-endogenous 6-hydroxydopamine is the cause of aggravated dopaminergic neurodegeneration in Parkinson's disease patients

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Primary defects in carnitine synthesis or transport (deficiency OCTN2, trimethyllysine dioxygenase, butyrobetaine dioxygenase) are observed in about 1020% of ASD patients

Future efforts should focus on clinical applications by addressing safety concerns, optimizing large-scale production, and securing regulatory approvals for new formulations