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Treatment is appropriate when used to alleviate menopausal symptoms, improve quality of life, and prevent complications of long-term estrogen depletion, such as vulvovaginal atrophy and osteoporosis

*Correspondence: Liwan Fu, [email protected] Hu, [email protected] This article was submitted to Clinical Nutrition, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

When this work was completed, she headed for the Caribbean to conduct two weeks of trials off Vieques Island, Puerto Rico