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A liberao natural de GLP-1 ocorre quando macronutrientes especficoscomo cidos graxos de cadeia curta derivados de fibras fermentveis, peptdeos de protenas e cidos graxos insaturadosentram em contato direto com os receptores sensoriais das clulas L no intestino, desencadeando a secreo imediata do hormnio para suprimir o apetite e liberar insulina