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A newly identified advantage of dual GIPR/GLP-1R agonists is their ability to reduce the adverse effects of nausea and vomiting, which are commonly associated with GLP-1RAs

Discussion Together, these studies examining oxidative stress, redox dysregulation, metabolic alterations, and neuroinflammation suggest that these processes are all not only involved in the pathogenesis of epilepsy, but fundamentally linked (See Scheme 1)

Researchers Analyzed Real-World Patient Outcomes The team used Optum Market Clarity, a US electronic health record and insurance claims database, to analyze patients who started liraglutide, semaglutide, or tirzepatide between January 2021 and June 2024

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