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In the SGZ, radial glia-like or type 1 cellsadult multipotent NSPCs also exhibit a multistep differentiation process as described for the SVZ niche, beginning with the expansion of type 2a cells (transient amplifying progenitor cells) (Seri et al., 2001

This imbalance can lead to oxidative-mediated central nervous system (CNS) damage, which is further supported by declined cognitive abilities and more severe depressive symptoms in these individuals

10.1016/j.cjca.2014.10.027 92 PeoplesJ

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69 In gastric cancer cells, the absence of CDO1 contributed to restore cellular glutathione levels, to prevent ROS and lipid peroxidation, and to promote resistance to ferroptosis, a type of programmed cell death dependent on iron and associated with lipid peroxide accumulation