ARA-290 selectively engages the innate repair receptor (IRR) and does not activate the classical EPO receptor responsible for erythropoiesis
Jeong Y-J, Park Y-Y, Park K-K, Choi YH, Kim C-H, Chang Y-C (2019) Bee venom suppresses EGF-induced epithelial-mesenchymal transition and tumor invasion in lung cancer cells
Improvement in quality of life after surgery for glomus tumors of the fingers
"GI AEs typically occur during initiation and uptitration, appearing as transient, mild-to-moderate symptoms." Laura Schalliol, PharmD, BCACP, BCGP, Professor of Pharmacy Practice In fact, 94% of adverse events reported in major clinical trials were mild or moderate in severity
However, when combined with insulin or sulfonylureas, hypoglycemia risk increases, and dose adjustments of these concomitant medications may be necessary