It enhances the activity of CREB, a transcription factor that regulates the expression of genes involved in memory consolidation, and promotes the production of BDNF, or brain-derived neurotrophic factor, a protein that acts as a kind of molecular fertilizer for neurons, supporting their survival, growth, and the formation of new synaptic connections [15]
doi: 10.1016/j.psj.2024.104432 332 McKayDLBlumbergJB
[5] Eli Lillys weight loss and diabetes drug tops Keytruda as worlds best-selling medicine, October 2025: 's%20tirzepatide%2C%20marketed%20as%20Mounjaro,date%20sales%20to%20$23.3%20billion
These factors typically resolve within 24 weeks as your body acclimates to the medication and you establish a sustainable eating pattern
However, patients may require another full course of therapy, or they may continue the therapy microdosing, as is being evaluated in other disease states, she said