The concept draws from hormesis, a biological phenomenon where low-dose exposure to a substance produces beneficial effects while higher doses might produce neutral or even counterproductive outcomes
Plant Physiol 150:825833 Ide Y, Kusano M, Oikawa A, Fukushima A, Tomatsu H, Saito K, Hirai MY, Fujiwara T (2011) Effects of molybdenum deficiency and defects in molybdate transporter MOT1 on transcript accumulation and nitrogen/sulphur metabolism in Arabidopsis thaliana
The GLP-1 (treatment) cohort was comprised of individuals who (i) had no prior history of GLP-1 use, (ii) initiated GLP-1 medications from January 2019 onwards with the prescription originating from a primary care provider or endocrinologist, and (iii) had medication orders indicating a minimum duration of 12 months of prescriptions
GLP-1 RAs are known to have a beneficial effect on lipid profile and blood pressure (BP)
It mimics the hormone GLP-1, which helps regulate blood sugar and appetite