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James LP, Simpson PM, Capperelli E, Roberts DW, Hinson JA, Davern TJ, Lee WM: Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure

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IGF-1 gene transfer to CCl 4 -induced rat models alleviates hepatocyte premature senescence and fibrogenesis To evaluate the effect of IGF-1 on hepatocyte premature senescence and liver fibrosis, IGF-1 lentiviral vector was transferred to CCl 4 -induced rat models to overexpress IGF-1 of liver