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For instance, a 24-hour urine output of 150 mg/day) represents a loss in the ability of the glomeruli in the kidney to selectively retain blood proteins, which ultimately leads to difficulties maintaining blood volume and is a powerful predictor of kidney failure (Cravedi 2013

(River Peptides) Thus FOXO4-DRI belongs to the next generation of senolytic tools with improved selectivity and lower collateral damage risk (at least in preclinical models)

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4.1 Interaction between fungal virulence factors and host mitochondria Fungal virulence factors directly target host mitochondria, profoundly disrupting bioenergetic and immune functions

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