glutathione depletion and autism Mercury-induced excitotoxicity in spectrum disorder: disruption of glutamatergic homeostasis the therapeutic role of the selenium– axis | BioMetals The Interplay of Oxidative Stress,

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References: Poljak, B., Dahmane, R

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Moreover, the activity of -glutamylcysteine synthetase (-ECS), which catalyses the first step of the committed GSH synthesis pathway, is regulated by oxidation, both at the level of oxidant-induced de-repression of -ECS translation and at the post-translational level by oxidation of enzyme thiol groups (Hicks et al ., 2007