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Reported concerns include gastrointestinal irritation, low potassium levels, and reduced bone mineral density with prolonged use

El GLP-1 ha servido de desarrollo de toda una familia farmacolgica (los arGLP-1), mientras que el GIP no ha conducido a un desarrollo similar, probablemente porque sus efectos insulinotrpicos estn alterados en las personas con DM2, a pesar de que los efectos insulinotrpicos del GIP pueden ser restaurados tras 4 semanas de normalizacin de la hiperglucemia con insulina en pacientes con DM2

That usually means prioritizing protein, doing simple strength training, and avoiding extreme calorie restriction that can backfire

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